Capital Signal

Clinuvel Pharmaceuticals Limited (ASX: CUV)

Sector: Health Care

Market cap: A$365M (as of 2 Nov 2026)

Clinuvel Pharmaceuticals Ltd. is a leading and innovative Australian company focused on the development of SCENESSE (afamelanotide), its proprietary first-in-class drug, as a photoprotective in a range of UV and light related skin disorders a

Data as of 2 Nov 2026.

Substantial holders — latest moves

DateHolderMoveHoldingSource
24 Sept 2026Vanguard Group (The Vanguard Group, Inc. and its controlled entities)Entry?% → 5.15%Filing ↗
2 Sept 2026Vanguard Group (The Vanguard Group, Inc. and its controlled entities including Vanguard Investments Australia Ltd.)Exit?% → 4.972%Filing ↗
14 Aug 2026Vanguard Group (The Vanguard Group, Inc. and its controlled entities)Entry?% → 5.003%Filing ↗
26 Apr 2022A.C.N. 108 768 896 PTY LTDExit—Filing ↗
22 Dec 2020Clinuvel Pharmaceuticals Ltd (ACN 089 644 119) (Company), A.C.N. 108 768 896 Pty Ltd (ACN 108 768 896), Clinuvel (UK) Ltd, Clinuvel, Inc, Clinuvel AG, Clinuvel Singapore Pte Ltd, Vallaurix Pte Ltd, Clinuvel Europe Ltd, Vallaurix MC SarlDecrease9.24% → 5.93%Filing ↗

Director trades — on-market

DateDirectorTradeSource
19 Sept 2023Dr Philippe WolgenBought 1,850Filing ↗
22 June 2023Dr Philippe WolgenBought 1,532Filing ↗
4 Nov 2022Jeffrey RosenfeldBought 300Filing ↗
16 June 2022Mrs Brenda ShanahanSold 15,000 Ordinary SharesFiling ↗
6 June 2022Mrs Brenda ShanahanSold 22,392 Ordinary SharesFiling ↗

Cash and runway

MetricValueAs ofSource
CashA$141M31 Dec 2022Filing ↗

Latest cash figure is from 31 Dec 2022 and may predate a later quarterly filing.

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